[{"@context":"https:\/\/schema.org\/","@type":"Article","@id":"https:\/\/www.kennels.cz\/pilulka-mode-barvy\/#Article","mainEntityOfPage":"https:\/\/www.kennels.cz\/pilulka-mode-barvy\/","headline":"Pilulka mod\u00e9 barvy","name":"Pilulka mod\u00e9 barvy","description":"Jedn\u00edm z l\u00e9\u010div, kter\u00e9 bude m\u00edt v podv\u011bdom\u00ed snad ka\u017ed\u00fd, je Viagra, jin\u00fdm n\u00e1zvem tak\u00e9 […]","datePublished":"2022-12-24","dateModified":"2023-06-05","author":{"@type":"Person","@id":"https:\/\/www.kennels.cz\/author\/#Person","name":"","url":"https:\/\/www.kennels.cz\/author\/","identifier":1,"image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/1aa4d33840e2afc29128e2a456d425ca0d17b173c888af2db652b1d34fe6f93d?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/1aa4d33840e2afc29128e2a456d425ca0d17b173c888af2db652b1d34fe6f93d?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"kennels.cz","logo":{"@type":"ImageObject","@id":"\/logo.png","url":"\/logo.png","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/www.kennels.cz\/wp-content\/uploads\/viagra-gd1465def4_640_1.jpg","url":"https:\/\/www.kennels.cz\/wp-content\/uploads\/viagra-gd1465def4_640_1.jpg","height":0,"width":0},"url":"https:\/\/www.kennels.cz\/pilulka-mode-barvy\/","wordCount":382,"articleBody":"   Jedn\u00edm z l\u00e9\u010div, kter\u00e9 bude m\u00edt v podv\u011bdom\u00ed snad ka\u017ed\u00fd, je Viagra, jin\u00fdm n\u00e1zvem tak\u00e9 Sildenafil. Jedn\u00e1 se o l\u00e9k, kter\u00fd se na trhu objevil pom\u011brn\u011b ned\u00e1vno, patentov\u00e1n byl v roce 1996 a k prvn\u00edm z\u00e1kazn\u00edk\u016fm se dostal a\u017e v roce 1998. O t\u00e9 doby si ale vybudoval velmi pevnou klientelu. Tento l\u00e9k jako prvn\u00ed p\u0159ipravila velmi dob\u0159e zn\u00e1m\u00e1, obzvl\u00e1\u0161\u0165 v posledn\u00ed dob\u011b, anglick\u00e1 farmaceutick\u00e1 firma Pfizer. I kdy\u017e zdej\u0161\u00ed t\u00fdm usiloval o l\u00e9ky na hypertenzi neboli vysok\u00fd tlak a na anginu pectoris, p\u0159i testov\u00e1n\u00ed l\u00e9ku zjistili, \u017ee u mu\u017esk\u00fdch \u00fa\u010dastn\u00edk\u016f studi\u00ed se objevil vedlej\u0161\u00ed efekt v podob\u011b erekce penisu. Nakonec tedy tento l\u00e9k nebyl pu\u0161t\u011bn do ob\u011bhu jako \u00fa\u010dinn\u00fd na kardiovaskul\u00e1rn\u00ed probl\u00e9my, ale jako \u0159e\u0161en\u00ed p\u0159i erektiln\u00ed dysfunkci.  Jak vlastn\u011b tento l\u00e9k funguje? Jedn\u00e1 se vlastn\u011b o inhibitor fosfodiester\u00e1zy, enzymu, kter\u00fd by, kdyby byl funk\u010dn\u00ed odstra\u0148oval l\u00e1tku, kter\u00e9 zjednodu\u0161en\u011b \u0159\u00edk\u00e1me cGMP. cGMP je mal\u00e1 molekula, kter\u00e1 funguje jako sign\u00e1l mezi r\u016fzn\u00fdmi bu\u0148kami. Tyto, pokud na cGMP, maj\u00ed specifick\u00fd receptor, m\u016f\u017eou za\u010d\u00edt vyr\u00e1b\u011bt oxid dusnat\u00fd (NO). Kdy\u017e budeme sledovat \u00fa\u010dinek oxidu dusnat\u00e9ho, uvid\u00edme, \u017ee funguje velmi podobn\u011b jako cGMP, tedy jako sign\u00e1ln\u00ed molekula, kter\u00e1 se v\u00e1\u017ee na receptory na hladk\u00fdch svalov\u00fdch bu\u0148k\u00e1ch (\u010dasto jsou tyto hladk\u00e9 svalov\u00e9 bu\u0148ky p\u0159\u00edtomny ve st\u011bn\u011b c\u00e9v a sv\u00fdm stahem ovliv\u0148uj\u00ed jejich pr\u016fm\u011br a tedy i pr\u016ftok krve). V moment\u011b, kdy hladk\u00e9 svalov\u00e9 bu\u0148ky uc\u00edt\u00ed na sv\u00fdch receptorech NO, dojde k jejich relaxaci, co\u017e vede ke zv\u00fd\u0161en\u00e9mu toku krve do topo\u0159iv\u00fdch t\u011bles penisu a k jeho erekci. V roce 2013 vypr\u0161el patent na tento l\u00e9k, tak\u017ee dnes je mohou pod r\u016fzn\u00fdmi n\u00e1zvy prod\u00e1vat r\u016fzn\u00e9 firmy. Viagra na prodej je ale t\u00edm p\u00e1dem dost ovlivn\u011bn\u00e1 svobodn\u00fdm trhem, tak\u017ee do obvykle vyplat\u00ed hledat tu nejlep\u0161\u00ed nab\u00eddku, jinak si m\u016f\u017eete za ten sam\u00fd produkt p\u0159iplatit i v\u00fdrazn\u011b vy\u0161\u0161\u00ed \u010d\u00e1stkou.                                                                                                                                                                                                                                                                                                                                                                                          4.9\/5 - (9 votes)        "},{"@context":"https:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"name":"Pilulka mod\u00e9 barvy","item":"https:\/\/www.kennels.cz\/pilulka-mode-barvy\/#breadcrumbitem"}]}]